Neurogenetics
Neurogenetics brings to bear the powerful tools of modern genetics and genomics to some of the most important and fascinating problems in all of biomedical sciences. UCLA is widely recognized as one of the leading centers of neurogenetics research. The breadth of the neurogenetics research program is extraordinary, ranging from investigations of invertebrate model systems within single laboratories to trans-disciplinary collaborative programs focused on complex human phenotypes, in the Consortium for Neuropsychiatric Phenomics. The Neurogenetics FAR is built around a well-established training structure and NIH-funded joint predoctoral and postdoctoral training programs in Neurobehavioral Genetics. These training programs exemplify the signature focus of the FAR; using genetics to integrate “neuro” and “behavioral” approaches to neuroscience investigation, with a particular emphasis on phenotyping of the nervous system-across systems from flies to humans-as a distinct scientific endeavor. Current faculty within the NIH-funded training programs represent a wide diversity of research interests and provide a broad range of opportunities for students. There is already an enormous level of interaction between faculty in the program, and this is enhanced by a yearly retreat, bi-monthly seminar series and a flexible core curriculum tailored to individual student backgrounds.
List of Faculty:
Akin, Orkun | Role of neural activity in brain development and synapse formation |
Alward, Beau | Neuroendocrinology of social behavior |
Arnold, Arthur | Sexual Differentiation of the Brain |
Balliu, Brunilda | Genetic basis of neuropsychiatric traits in humans. |
Bearden, Carrie | Neurodevelopmental Disorders; Cognition, Neuroimaging and Genetics of Mood Disorders and Psychosis |
Bilder, Robert | Neuropsychology and Neuroimaging |
Black, Douglas | Post-transcriptional Gene Regulation in Neurons |
Bookheimer, Susan | Functional Neuroimaging of Language and Memory |
Butler, Samantha | Generating and regenerating neural circuitry in the spinal cord |
Correa, Stephanie | Neural control of energy homeostasis, estrogen signaling, neuroendocrinology |
Daboussi, Lydia | Mechanisms of Plasticity for Neural Repair |
Dapretto, Mirella | Neuroimaging/imaging genetics of language and social cognition in typical and atypical development (emphasis on adolescence and autism spectrum disorders); cultural neuroscience |
de la Torre-Ubieta, Luis | Mechanisms of human neocortical development and neuropsychiatric disease using neural stem cell models and bioinformatic approaches. |
DeNardo, Laura | Assembly and function of neural circuits underlying adaptive behaviors |
Deters, Kacie | Risk factors for cognitive decline and dementia in Black individuals |
Donlea, Jeffrey M. | Sleep regulation, learning and memory |
Flint, Jonathan | Genetic basis of anxiety and depression in animal models and in humans |
Fogel, Brent | Exploring the Molecular Basis of Neurodevelopmental and Neurodegenerative Disease |
Freimer, Nelson | Identifying Genes that Contribute to Predisposition to Complex Human Phenotypes |
Geschwind, Daniel | Neurogenetics, Systems Biology of Neurodevelopmental (e.g. Autism) and Neurodegenerative Disorders (Dementia and Ataxia) |
Guo, Ming | Studying Mechanisms of Neurodegenerative Disorders in Drosophila |
Hallem, Elissa | Olfactory Behavior in Free-living and Parasitic Nematodes |
Hernandez, Leanna | Psychiatric genetics, neuroimaging, neurodevelopmental disorders (e.g., autism, schizophrenia, ADHD) |
Hoftman, Gil | Understanding psychosis risk using neuroimaging and genetics |
Hong, Weizhe | Neural Mechanisms of Social Behavior |
Hsiao, Elaine | Neurobiology of disease, neuroimmunology, microbiome-nervous system interactions |
Kaufman, Daniel | Therapeutics for diabetes and neurological disease |
Krantz, David | Using Drosophila to Study Neurotransmitter Transport, Synaptic Transmission, Behavior and Disease |
Leuchter, Andrew | Neurophysiology of Depression; Neurophysiologic Predictors of Treatment Outcome |
Loo, Sandra | Gene-Brain-Behavior Pathways in Childhood Psychiatric Disorders |
Martin, Kelsey | Cell Biology of Learning-related Synaptic Plasticity |
Mendizabal, Adys | Study of social and structural determinants of health and its impact in neurological outcomes: Health Disparities in Huntington’s Disease and Adverse Childhood Experiences across different neurological conditions |
Nathanson, David | Research and drug development for malignant brain tumors |
Nurmi, Erika | Pharmacogenomic factors in treatment of autisim, ADHD, anxiety and depression |
Olde Loohuis, Loes | The identification of genetic and environmental variables that contribute to the cause and course of psychiatric illness |
Ophoff, Roel | Human Genetic Studies of Neuropsychiatric Traits |
Portera-Cailliau, Carlos | Imaging the Assembly and Plasticity of Cortical Circuits with Two Photon Microscopy |
Sagasti, Alvaro | Development of Complex Cell Shapes in Zebrafish Touch-Sensing Neurons |
Silva, Alcino | Molecular and Cellular Mechanisms of Learning and Memory |
Smith, Desmond | Functional Neurogenomics |
White, Stephanie | Social Influences on Learning and Memory |
Williams, David | Retinal Cell Biology, Sensory Neuroscience, Neurodegeneration |
Woods, Roger | Structural and Functional Brain Imaging |
Wu, Ye "Emily" | Neural basis of empathy and prosocial behavior |
Yang, X. William | Mouse Genetic Approach to Study the Pathogenesis of Neurodegenerative Diseases |
Zhang, Chuchu | Neural mechanisms of internal sensations i.e. how we feel inside our body, with a focus on the molecular and circuit mechanisms of nausea. |
Zhang, Ye | Glia biology in health and disease |
Zipursky, Larry S. | Molecular Mechanisms Regulating Neuronal Circuit Assembly |